Epidemiology and Etiology of MS

MS is the most common inflammatory disease of the CNS, affecting an estimated 2,500,000 people worldwide and 350,000 in the United Sates alone (Johnson, 1994) (Kantarci 

Two or more attacks objective clinical evidence of two or more lesions 

Two or more MRI-detected lesions consistent with M.S plus positive C.SF or 

Two or more MRl-detected lesions consistent with MS plus positive CSF or 

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