Enzymes, direct electron transfer catalase

The direct electron transfer from the coenzyme NADH to the electrode can be facilitated using organic conducting salts such as NMP+TCNQ" (see 3.3.l.f). These salts reduce the cofactor redox potential required, which limits any interference phenomena and fouling up of the electrodes [43]. These problems can also be overcome using an electrode with a hydrophobic membrane (p02 electrode) on which alcohol oxidase and catalase [170] can be immobilized. These enzymes catalyse the following reactions ... 

Moreover, it has been demonstrated that CNTs promote the direct electrochemistry of enzymes. Dong and coworkers have reported the direct electrochemistry of microperoxidase 11 (MP-11) using CNT-modified GC electrodes [101] and layer-by-layer self-assembled films of chitosan and CNTs [102], The immobilized MP-11 has retained its bioelectrocatalytic activity for the reduction of H202 and 02, which can be used in biosensors or biofuel cells. The direct electrochemistry of catalase at the CNT-modified gold and GC electrodes has also been reported [103-104], The electron transfer rate involving the heme Fe(III)/Fe(II) redox couple for catalase on the CNT-modified electrode is much faster than that on an unmodified electrode or other... 

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