Enzyme-catalyzed synthesis of amino acid derivatives

5 Enzyme-catalyzed synthesis of amino acid derivatives 

Covalent attachment of the a-carboxyUc add moiety of CBz-protecled amino acids with alcohols or amines has been the most successful approach for enzymic transformations. The attempt to add fatty acyl groups to free amino acids has not been successful (Soo et al., 2003 Valivety et al., 1997). The most successful addition of acyl groups to unprotected amino acids has been reported for the e-amino group of lysine, the e-OH group of homoserine. 

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