Entropies of hydration at infinite dilution, AS

A5 is always large and negative for hydrophobic hydration. This supports the belief that dissolution must increase the order of the solution, which, in turn, suggests the alteration in structure which would result from cage formation. 

This is a change in volume at infinite dilution when the solute and solvent are mixed to give the 

Such studies show found that A is always negative for hydrophobic hydration. If the solute is small then it can fit into the spaces of the normal tetrahedral H-bonded structure of ordinary water, giving a decrease in volume. But if cage structures result it could be expected that the water structure is even more compacted around the solute, resulting in a further decrease in volume. 

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