Enolate Complexes Written with Prof. Erik J. Alexanian

Enolate Complexes (Written with Prof. Erik J. Alexanian) 

Transition metal enolate complexes have been prepared with most or all transition metals, and the enolate ligands have been shown to adopt a variety of bonding modes. Bofli early and late transition metal enolate complexes are intermediates in a number of important catalytic processes. Early transition metal enolates are important intermediates in asymmetric aldol reactions that exploit the Lewis acidic character of early metals. Late transition metal enolates are intermediates in aldol and Michael addition processes, -Saegusa oxidations,Heck-type processes, catalytic asymmetric conjugate additions, - and cross coupling of enolate nucleophiles. -  

This section includes the synthesis and structures of bothC-bound and Obound transition metal enolate complexes. Reviews of reactions catalyzed by Lewis acidic, early metal enolate intermediates have been published. Cross-couphng of enolates is described in Qiapter 19. Additional reactions of enolate nucleophiles, such as enolate allylation, are ttiought to occur by external attack of the enolate nucleophile on -ir-ligands and are described in Chapters 11 and 20. Late transition metal enolate complexes undergo a number of the classes of stoichiometric reactions presented in Chapters 3-12 of this text, including 3-hydride elimination to produce enones, - insertion of unsaturated ir-systems, and reductive eluninations. - - -  

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