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Endogenous antioxidant mechanisms and

A variety of other metals and their complexes have been studied for radioprotective activity. Among these are copper glycinate, strontium chloride, ZnNa -diethylenetriaminepentaacetate (ZnDTPA), and selenium, which has been studied because of its relationship to endogenous antioxidant mechanisms, especiaHy GSH peroxidase and vitamin E. [Pg.491]

Seibig S, van Eldik R (1997) Kinetics of F e (11) EDTA oxidation by molecular oxygen revisited. New evidence for a multistep mechanism. Inorg Chem 36 4115-4120 SimandanT, Sun J, DixTA(1998) Oxidation of DNA bases,deoxyribonudeosides and homopolymers by peroxyl radicals. Biochem J 335 233-240 Spinks JWT, Woods RJ (1990) Introduction to radiation chemistry. Wiley, New York Strohmeier Gort A, Imlay JA (1998) Balance between endogeneous superoxide stress and antioxidant defenses. J Bacteriol 180 1402-1410... [Pg.46]

An appropriate equilibrium between oxidation and antioxidants is fundamental for life. Antioxidants and OS can be understood only through the knowledge of the mechanisms that generate oxidation and the activity of both endogenous antioxidants and those that are made available by food intake or its supplementation. [Pg.211]

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