Endocervical adenocarcinoma in situ

FIGURE 18.8 Endocervical adenocarcinoma in situ may mimic reactive, inflamed surface epithelium (A) (H E) however it is distinguished by diffuse MIB1 expression (B) and diffuse pi 6 expression (C). These markers highlight the typical abrupt transition between normal and neoplastic epithelium. 

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