Enantioselective Conjugate Addition Reactions via Hydrogen-bonding Activation

Enantioselective Conjugate Addition Reactions via Hydrogen-bonding Activation 

Organocatalytic Enantioselective Conjugate Addition Reactions A Powerful Tool for the 

By Jose L. Vicario, Dolores Badia, Luisa Carrillo and Efraim Reyes 

Moreover, calculations also suggested that the final product only participated in a single hydrogen bonding with the catalyst, resulting in a weaker interaction and therefore providing an explanation for the catalyst turnover. This study set the basis for the subsequent development of a wide family of chiral thioureas. 

1 Some Relevant Aspects Influencing the Stereocontrol in Michael Additions Proceeding via Hydrogen-honding Activation 

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