Enantiomer recognition catalytic reactions

By contrast with the enantioselective deprotonation of meso oxiranes, there is only a limited number of reports on the kinetic resolution of unsymmetrically substituted oxiranes. This reaction involves the preferential recognition of one of the two enantiomers of a racemic mixture by a chiral reagent to provide both the starting material and the product in enantioenriched form . Several HCLA bases developed for enantioselective deprotonation have been tested as chiral reagent in stoichiometric or catalytic amount for the kinetic resolution of cyclic and linear oxiranes. 

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