Ticlopidine Enalapril

Cardiovascular Acetyldigosin, ajmaline, amiodarone, aprindine, bepridil, bezaflbrate, captopril, dinepazide, clopidogrel, coumarins, diazoxide, digoxin, dipyridamole, disopyramide, doxazosin, enalapril, flurbiprofen, fur-oxemide, hydralazine, lisinopril methyldopa, metolazone, nifedipine, phenindione, procainamide, propanolol, propafenone, quinidine, ramapril, spironolactone, thiazide diuretics, ticlopidine, vesnarinone... 

Enalapril, paracetamol, sotalol, dipyrone, vancomycin, captopril, fluconazole, cefazolin, metoprolol, aspirin, ticlopidine, prednisolone, propranolol, digoxin, sildenafil, furosemide, dexamethasone, carvedilol, ketoprofen, nifedipine, terbinafine, acenocoumarol, spironolactone/urine HPLC DAD Column LiChroCART Purospher STAR, RP-18e (250 x 4 mm, 5 pm) Mobile phase MeOH ACN 0.05 % TFA in water (gradient elution) Detection DAD X = 200 50 nm Adjusted to pH 7.0, protein precipitation LOD 0.01-1.44 pg/mL LOQ 0.04-4.35 pg/mL [72]... 

Milrinone, enalapril, carvedilol, spironolactone, acenocumarol, ticlopidine, cilazapril, 2-oxoticlopidine, cilazaprilat, canrenone, 5 -hydroxycarvedilol, 0-desmethylcarvedilol, enalaprilat/urine UHPLC UV Column Poroshell 120 EC-Cig (100 X 3.0 mm 2.7 pm) Mobile phase Solvent A 0.05 % TEA in water Solvent B ACN (gradient elution) Detection 2 = 227, 235, 255, 269, 285, 324 nm Extraction MBPS/ sorbent C18/elution MeOH ACN (50 50 v/v) LOQ 0.016-0.045 pg/mL [76]... 

Spaulding C, Charbonnier B, Cohen-Solal A, Juilliere Y, Kromer EP, Benhamda K, Cador R, Weber S. Acute hemodynamic interaction of aspirin and ticlopidine with enalapril results of a double-blind, randomized comparative trial. Circulation 1998 98(8) 757-65. 

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