Emulsification assay

The resulting SILMs were stable under assayed conditions. These authors highlighted the importance of the consideration of two main possible effects on the performance and stability of SILMs in water mediums (a) the loss of ionic liquids phase from the supporting membrane to the adjacent aqueous solutions by dissolution/ emulsification and (b) the formation of water microenvironments inside the ionic liquids phase, which constitute new, non-selective environments for solute transport, leading to a deterioration of the SLM performance and selectivity. 

Perform globule size assay to check the uniformity of emulsification on each product blend as per SOP. 

Some care is required during the preliminary extraction stage of the assay to avoid serious emulsification. 

The extraction of the alkaloids from cinchona is difficult and, as the bark contains colouring matter and substances which cause emulsification, the quantitative determination is not easy. A continuous extraction assay is needed, such as that of Self and Corfield this is probably the most satisfactory process. 

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