Elimination half life post-infusion data

Determination of the elimination half life (fi/a), the elimination rate constant (K oiKd) and the apparent volume of distribution (V) from post-infusion (i.e. following the cessation of infusion) concentration versus time data and from concentration versus time data obtained during infusion. 

Half life, elimination rote constant and the apparent volume of distribution from the post-infusion data and by the graphical method... 

The Rowland and Tozer method allows the elimination half life and elimination rate constant to be calculated for an administered drug by using plasma concentration-time data obtained during the infusion period (i.e. plasma concentration values in the post-infusion period are not required). 

Use of post-infusion plasma concentration data to obtain half life, elimination rate constant and the apparent volume of distribution... 

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See also in sourсe #XX -- [ , , , , ]

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