Ehrlich magic bullet approach

Scientists such as Paul Ehrlich, searching for an antisyphilitic, have exemplified the idea of serial screening of compounds in an attempt to find a "magic bullet." This approach, although tedious and time consuming, did generate a remarkable number of drugs, such as the benzodiazepines, chlorpromazine, and others (14). 

Drug targeting with MAbs has always been a fascinating theoretical approach to the rational treatment of acquired diseases such as cancer, according to the concept of Magic Bullets - a term created by Paul Ehrlich who suggested the couphng of toxic natural compounds to specific vectors that are able to find their way to the disease and thereby increase the pharmaceutical index [104]. 

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