Effect of Silica Nanomaterial Size

A smaller size not only facilitates the cellular uptake and translocation of nanomaterials but also alters the interaction between nanomaterials and the cellular components. Changes in particle-protein interaction appear to influence silica nanomaterial-induced toxidty [69, 72, 74,80,102], as demonstrated in the pioneer studies reported in 2004 of the interaction between silica nanopartides and pro- 

Reprinted with permission from Ref 82] 2007, American Chemical Society. 

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