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E-Pyrromycinone

The trisaccharide chain in Cinerubin A, an anthracycline antibiotic with antimitotic activity, has been replaced by a poly(ethylene glycol) The resulting poly(ethylene oxide)-bound e-pyrromycinone is readily soluble in water and exhibits full biological activity. In this case, the hydrophilic poly(ethylene oxide) chain appears to be perfectly suitable to simulate the physicochemical properties of the oligosaccharide chain. [Pg.84]

See other pages where E-Pyrromycinone is mentioned: [Pg.373]    [Pg.190]    [Pg.47]    [Pg.145]    [Pg.161]    [Pg.127]    [Pg.132]    [Pg.44]    [Pg.127]    [Pg.132]    [Pg.103]    [Pg.111]    [Pg.373]    [Pg.190]    [Pg.47]    [Pg.145]    [Pg.161]    [Pg.127]    [Pg.132]    [Pg.44]    [Pg.127]    [Pg.132]    [Pg.103]    [Pg.111]    [Pg.128]    [Pg.578]   
See also in sourсe #XX -- [ Pg.11 , Pg.120 ]



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E-Pyrromycinone via cyclofunctionalization of cycloalkene

Pyrromycinones

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