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E1A protein

Shi, Y., Seto, E., Chang, L. S. and Shenk, T. (1991). Transcriptional repression by YY1, a human GLI-Kruppel-related protein, and relief of repression by adenovirus E1A protein. Cell 67, 377-388. [Pg.17]

Whyte P, Williamson NM, Harlow E. 1989. Cellular targets for transformation by the adenovirus E1A proteins. Cell 56 67-75... [Pg.67]

Two of the most commonly affected genetic loci in human tumors are the tumor suppressor genes p53 and pRb or other components in the respective pathways. Both protein activities must be eliminated from the host cell in case of a productive adenoviral infection. This is normally brought about by proteins encoded by the adenoviral E1A and E1B genes. Therefore, adeno-viral mutants lacking one of these proteins should be unable to replicate efficiently in normally cells, but should be able to do so in p53- or pRb-deficient tumor cells. [Pg.276]

Viral protein Adenoviral E1A, large T antigen, HIV Tat, s-HDAg... [Pg.697]

See other pages where E1A protein is mentioned: [Pg.436]    [Pg.125]    [Pg.53]    [Pg.436]    [Pg.125]    [Pg.53]    [Pg.16]    [Pg.286]    [Pg.22]    [Pg.564]    [Pg.580]    [Pg.582]    [Pg.54]    [Pg.424]    [Pg.85]    [Pg.456]    [Pg.151]    [Pg.156]    [Pg.160]   
See also in sourсe #XX -- [ Pg.408 , Pg.440 ]

See also in sourсe #XX -- [ Pg.53 ]



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