Drug synthesis redox enzymes

Introduction. Glutathione (36) (Fig. 13.31, GSH) is a thiol-containing tripeptide of major significance in the detoxification and toxification of drugs and other xenobiotics (78). In the body, it exists in a redox equilibrium between the reduced form (GSH) and an oxidized form (GS-SG). The metabolism of glutathione (i.e., its synthesis, redox equilibrium, and degradation) is quite eomplex and involves a number of enzymes (79, 80). 

APPLICATION OF SELECTED REDOX ENZYMES IN DRUG AND NATURAL PRODUCT SYNTHESIS... 

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