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Drug design lipophilic compounds

Although experimental partition coefficients are the values of reference, drug design often necessitates log evaluations before the compound has been synthesized. Consequently, various methods have been developed to predict lipophilicity [188], and they generally apply only to neutral compounds in the water-OCT system. [Pg.737]


See other pages where Drug design lipophilic compounds is mentioned: [Pg.492]    [Pg.6]    [Pg.501]    [Pg.382]    [Pg.271]    [Pg.139]    [Pg.438]    [Pg.44]    [Pg.52]    [Pg.59]    [Pg.1]    [Pg.25]    [Pg.38]    [Pg.91]    [Pg.18]    [Pg.100]    [Pg.6]    [Pg.78]    [Pg.413]    [Pg.506]    [Pg.184]    [Pg.544]    [Pg.589]    [Pg.1245]    [Pg.192]    [Pg.26]    [Pg.43]    [Pg.117]    [Pg.137]    [Pg.77]    [Pg.528]    [Pg.179]    [Pg.609]    [Pg.193]    [Pg.195]    [Pg.137]    [Pg.259]    [Pg.483]    [Pg.677]    [Pg.17]    [Pg.562]    [Pg.563]    [Pg.507]    [Pg.531]    [Pg.434]    [Pg.5]    [Pg.53]    [Pg.116]    [Pg.248]   
See also in sourсe #XX -- [ Pg.455 ]




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