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Drug delivery carborane

Thomas and Hawthorne have synthesized unimolecular, nanospherical boron-rich dodeca(carboranyl)-substituted closomers (122) (Fig. 71) for their potential application as drug-delivery platforms for BNCT.148 The substituted closomers were synthesized by reacting carborane acid chloride with the dodecahydroxy dodecaborate closomer in methylene chloride by utilizing a threefold excess of the former in triethylamine. The twelve pendant closo-1,2-carborane units in the closomer could... [Pg.72]

Yinghuai Z, Peng AT, Carpenter K, Maguire JA, Hosmane NS, Takagaki M (2005) Substituted carborane-appended water-soluble single-wall carbon nanotubes New approach to boron neutron capture therapy drug delivery. J. Am. Chem. Soc. 127 9875-9880. [Pg.50]


See other pages where Drug delivery carborane is mentioned: [Pg.5]    [Pg.239]    [Pg.156]    [Pg.171]    [Pg.203]    [Pg.676]    [Pg.708]    [Pg.718]    [Pg.854]    [Pg.68]    [Pg.239]    [Pg.150]    [Pg.196]    [Pg.10]   
See also in sourсe #XX -- [ Pg.36 ]




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