Droplet asymmetric particles

The intensity function is easily derived from A(q) as the square of its modulus (Figure 21.le). Note that for asymmetric particles such as droplet-shaped particles, the amplitude function is complex, while the intensity function is always... 

Similarly, Lan et al. [7] developed a one-step microfluidic method for fabricating nanoparticle-coated patchy particles. A coaxial microfluidic device was employed to produce Janus droplets composed of curable phase and non-curable phase. The results showed that nanoparticles were dispersed either in the continuous fluid or the non-curable phase fluid. The nanoparticles (30 nm or 300-500 nm) were adsorbed onto the interface between these phases, and the curable phase was solidified by UV-irradiated polymerization. Thus, the patchy microparticles asymmetrically coated by nanoparticles were synthesized. They also employed Si02, TS-1, and fluorescent polystyrene nanoparticles as the coating materials to demonstrate the validity of the method. The microfluidic approach exhibited excellent controllability in morphology, monodispersity, and size for the nanocomposites. The morphology of the particles could be controlled from less than a hemisphere to a sphere by adjusting the flow rate ratio of the two dispersed phases. The method can be applied to other nanoparticles with specific surface properties. 

Asymmetrical flow field-flow fractionation was used for size determinations of SLN in comparison to an emulsion and oil-loaded SLN. The differences found in the sizes and elution profiles were attributed to differences in the particle shapes. Due to their anisometric, platelet-like shape it is likely that SLN are more retained by the cross flow applied compared to spherical emulsion droplets. This method appears very promising as additional size determination method particularly with regard to separation and detection of different colloidal structures. 

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