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Doxorubicin-galactosamine

Figure 3 HPMA copolymer-anticancer conjugates. Panel (a) HPMA copol3mier-doxorubicin (PKl, FCE28068) panel (b) HPMAcopolymer-doxorubicin-galactosamine (PK2, FCE28069) panel (c) HPMAcopoly-mer-paclitaxel panel (d) HPMA copolymer-camptothecin. Figure 3 HPMA copolymer-anticancer conjugates. Panel (a) HPMA copol3mier-doxorubicin (PKl, FCE28068) panel (b) HPMAcopolymer-doxorubicin-galactosamine (PK2, FCE28069) panel (c) HPMAcopoly-mer-paclitaxel panel (d) HPMA copolymer-camptothecin.
HPMA copolymer-doxorubicin-galactosamine (Amide) PK2, FCE 28069 UK Cancer Research Campaign/ Pfizer Inc. Phase 1/11 [15,85]... [Pg.20]

Figure 1. Images of a patient with hepatoma taken from the Birmingham clinical studies, courtesy of P J Julyan. Top left X-ray CT image through the uppo abdomen. Top right SPECT image of I-HPMA-doxorubicin-galactosamine conjugate t en at the same level as the CT image. Bottom Fused anatomical and functional images. Figure 1. Images of a patient with hepatoma taken from the Birmingham clinical studies, courtesy of P J Julyan. Top left X-ray CT image through the uppo abdomen. Top right SPECT image of I-HPMA-doxorubicin-galactosamine conjugate t en at the same level as the CT image. Bottom Fused anatomical and functional images.
P = HPMA copolymer backbone ADR = adriamycin (doxorubicin) gal = galactosamine bound via the NH2 group... [Pg.107]

C. Young, A.M. Hesslewood, S. Morrison, R. Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine. Journal of Controlled Release 1999, 57, 281-290. [Pg.1337]

Configliacchi E, Razzano G, Rizzo V, Vigevani A. HPLC methods for the determination of bound and free doxorubicin and of bound and free galactosamine in methacrylamide polymer-drug conjugates. J Pharm Biomed Anal 1996 15 123-129. [Pg.75]

See other pages where Doxorubicin-galactosamine is mentioned: [Pg.52]    [Pg.22]    [Pg.25]    [Pg.22]    [Pg.25]    [Pg.52]    [Pg.22]    [Pg.25]    [Pg.22]    [Pg.25]    [Pg.108]    [Pg.388]    [Pg.242]    [Pg.24]    [Pg.237]    [Pg.9]    [Pg.18]    [Pg.57]    [Pg.125]    [Pg.63]    [Pg.19]    [Pg.25]    [Pg.203]    [Pg.19]    [Pg.25]   
See also in sourсe #XX -- [ Pg.52 ]



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