Double-network cryogels

Means of increasing the binding capacity include grafting, formation of composites, crosslinked nanoparticles with affinity, and double cryogel networks. 

Fig. 14 Preparation of cryogels with double-continuous macroporous networks and gradient porosity...

Cryogels with unique double-continuous macroporous networks have been prepared by a sequential process. First, one cryogel is prepared according to regular procedures. After thawing, the porous volume of the gel is filled with a new solution of monomers and catalysts before the gel is frozen once more. After this second polymerization and subsequent thawing, a gel is obtained with two interlacing polymer networks (Fig. 14). The procedure can be repeated more times. The effect... 

Plieva FM, Ekstrom P, Galaev lY, Mattiasson B (2008) Monolithic cryogels with open porous structure and unique double-continuous macroporous networks. Soft Matter 4 2418-2428... 

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