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Domino allylic substitution/carbocyclization

Scheme 2-93. Rh-eatalyzed domino allylic substitution/carbocyclizations. Scheme 2-93. Rh-eatalyzed domino allylic substitution/carbocyclizations.
Another domino cuprate 1,4-addition-initiated threefold anionic domino sequence was developed by Chemla and coworkers (Scheme 2.93) [214]. Michael addition of the a, 3-unsaturated ester 2-387 with PhCu(CN)ZnBr was followed by a carbocyclization to give the zinc species 2-388 which can be intercepted by iodine or an allyl bromide affording substituted pyrrolidines 2-389 and 2-390, respectively. [Pg.110]

See other pages where Domino allylic substitution/carbocyclization is mentioned: [Pg.259]    [Pg.214]    [Pg.218]    [Pg.263]    [Pg.259]    [Pg.214]    [Pg.218]    [Pg.263]    [Pg.191]   
See also in sourсe #XX -- [ Pg.263 ]

See also in sourсe #XX -- [ Pg.263 ]



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Allylic carbocycles

Allylic substitution

Domino allylic

Substituted carbocycles

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