Dome Matrix

Keywords Acrylic add polymers, cellulose derivatives. Dome Matrix, polyethylene oxide, polymethacrylates... 

The Dome Matrix is constituted of a cylindrically shaped tablet, with one of the bases concave and the other convex [1]. Principally, the individual modules are designed to allow the convex base of one module to be inserted into the concave base of another. The axial section of each module appears as a dome, hence such assembly is named Dome Matrix. The assembly of two adjacent modules is mediated via frictional interlocking. The basic modules differ in their concave base design. The male model is characterized by an annular protrusion on the concave rim base, whereas the female model exhibits a concave base that receives the annular protrusion of the male model (Figure 7.2) [1]. 

M. Casas, et al. Tapioca starch graft copolymers and Dome Matrix modules assembhng technology. I. Effect of module shape on drug release, Eur. J. Pharm. Biopharm., 75 (1),... 

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