Do We Compare Methods or Their Implementations

Our analysis included three LSER-like models. Two of them were provided by Pharma Algorithms and differed only with respect to the used regression coeffi- 

2 log P values were calculated at the http //www.vcclab.org site. 

3 VLOGP results for 257 molecules inside the OPS are shown in parentheses. 

4 90 molecules (including 79 with experimental values in TLOGP and 11 molecules that were not calculated) 

8 log values assuming an ionic strength of 0.1 were calculated for zwitterions. 

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