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DNA adduct detection

Figure 3. Structure of major DNA adduct detected in many in vivo systems as a result of metabolic activation of benzo[a]pyrene or the reaction of anti-B[alPDE with DNA jji vitro dR=deoxyribose moiety. Figure 3. Structure of major DNA adduct detected in many in vivo systems as a result of metabolic activation of benzo[a]pyrene or the reaction of anti-B[alPDE with DNA jji vitro dR=deoxyribose moiety.
Histologic and skeletal abnormalities in all BaP-exposed groups depressed mitotic rates in retina and brain in groups exposed to 0.08 pg/L and higher muscle necrosis in all groups exposed to 0.2 pg/L and higher microphthalmia was observed in 17% of BaP-treated trout No DNA adducts detected in liver... [Pg.1378]

Subadults fed diets for 6 days containing either 58 or 288 pg BaP daily, equivalent to 43 mg/kg BW or 216 mg/kg BW Liver DNA adducts detected in both cases 19... [Pg.1379]

Halbrook RS. Kirkpatrick RL, Bevan DR. 1992. DNA adducts detected in muskrats by P-postlabeling analysis. Environ Toxicol Chem 11 1605-1613. [Pg.473]

Vahakangas K, Trivers G, Rowe M. et al. 1985. Benzo[a]pyrene diolepoxide-DNA adducts detected by synchronous fluorescence spectrophotometry. Environ Health Perspect 62 101-104. [Pg.515]

Randerath, K., and Randerath, E. (1994). 32P-postlabeling methods for DNA adduct detection Overview and critical evaluation. Drug Metab Rev 26, 67-85. [Pg.355]

Singh, R., and Farmer, P. B. (2006). Liquid chromatography-electrospray ionization-mass spectrometry The future of DNA adduct detection. Carcinogenesis 27, 178-196. [Pg.356]

Whong, W. Z., Stewart, J. D., and Ong, X (1992). Comparison of DNA adduct detection between two enhancement methods of the 32P-postlabelling assay in rat lung cells. Mutat Res 283, 1-6. [Pg.358]

Endo Y, Hara I. 1991. DNA-adduct detection in rats administered with 4,4 -methylenedianiline or 4,4 -methylenebis(2-chloroaniline). J Ind Health 33 430-431. [Pg.123]


See other pages where DNA adduct detection is mentioned: [Pg.1378]    [Pg.1378]    [Pg.1379]    [Pg.808]    [Pg.31]    [Pg.30]    [Pg.73]    [Pg.315]    [Pg.158]    [Pg.139]    [Pg.64]    [Pg.64]    [Pg.411]    [Pg.206]    [Pg.373]   
See also in sourсe #XX -- [ Pg.189 ]




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DNA detection

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