Dithiolate-based Z-selective catalysts

A second design strategy based on choice of anionic ligand has proved successful in achieving Z-selective Ru-based metathesis catalysts by the Hoveyda group [37]. In contrast to the previous strategy, the selectivity of these catalysts relies on the formation 

Rgure 15 Catechol- and dithiolate-based Z-selective catalysts 

Z-selectivities in all cases were high ( 88% Z) and for many substrates the Z-product was formed essentially exclusively ( 98% Z). 

---