Diterpenoids interconversions

Chemical Conversion of Kobusine.—In their studies of diterpenoid interconversions, Okamoto and co-workers have reported the conversion of kobusine (113) into the amine (114) (Scheme 1). Chlorination of (114) with iV-chlorosuccinimide... 

The chemistry of the Daphniphyllum alkaloids has focused on the biogenetic aspects of their occurrence. The search for proposed biosynthetic intermediates among the minor alkaloids of these plants has resulted in the isolation and structure elucidation of five new bases. Accomplishments have included interconversions of the Daphniphyllum alkaloids by bond formation or fission. The compounds isolated thus far have been divided into five structural types and are reviewed as diterpenoids... 

Interconversions among Rabdosia diterpenoids have been frequently undertaken to establish the structures of new compounds, but were occasionally carried out as a matter of purely chemical interest. The following discussion is limited to interconversions between kaurene-type and 6,7-secokaurene-type diterpenes. The transformations are divided into biogenetic-type and retrobiogenetic-type chemical conversions. 

Gonzalez, AG., Alvarez, M.A., Martin, J.D., Norte, M., Perez, C., and Rovirosa, J. (1982) Diterpenoids of mixed biogenesis in Phaeophyta biogenetic-type interconversions. Tetrahedron, 38, 719-728. 

Shin, J. and Fenical, W. (1991b) New diterpenoids from the Caribbean gorgonian Eunica calyculata. Photochemical interconversion of the cembrane and cubitene skeletons./. Org. Chem., 56,1227-1233. 

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