Dissolution media compatibility with

Usually, when using HPLC, the standards and samples are prepared in a dissolution medium. However, to resolve compatibility issues between the medium and the mobile phase, the standards and samples may sometimes be diluted with mobile phase or a component of the mobile phase. ... 

When the aqueous solubility of an active substance is too low, it can be dissolved in a different solvent or mixture of solvents, which is compatible with the route of administration. The solubility of a lipophilic substance (a substance which dissolves well in the oil or fat but poorly in water) can be increased by making the dissolution medium (water) less polar by the addition of less polar but water-miscible solvents. Often mixtures of water, ethanol and propylene glycol are used. Also glycerol and macrogol (polyethylene glycol) can be used. The polarity of a solvent can be expressed by its dielectric constant, e (for examples see Table 18.8, the higher the dielectric constant, the higher the polarity). 

Whilst numerous literature methods exist to separate chlorine and iodine, many of these are not ideal for a commercial laboratory. They often rely on the use of relatively hazardous chemicals that require particular means of disposal, such as carbon tetrachloride in solvent extraction methods . In addition, the processes can be labour intensive, such as methods employing a speciation change of iodine as well as solvent extraction washes with chemicals such as sodium metabisulfite (Na2S205) °. In addition the dissolution of Agl in order to provide a more suitable medium for liquid scintillation counting can present difficulties as many of the techniques for dissolving Agl involve the use of relatively hazardous chemicals such as alkali cyanides, or the chemicals (and/or their required concentrations) are not compatible with liquid scintillation cocktails. 

The chemical properties of the CEP structure determine the ability to recognize particular stimuli and respond to them appropriately. In addition, these properties determine how the conducting polymer interacts with other materials in the construction of composite intelligent material structures. Most polymers are capable of, and indeed do, interact with other molecules. Such molecules may be part of larger molecular structures (important in the area of compatible materials), or they may be solvent molecules (such interaction can influence many processes including dissolution) or specific molecules in a solvent or gaseous medium. 

---