Dismutase Activity of Other Copper Enzymes

Human ceruloplasmin inhibits lipid autoxidation induced by ascorbate or inorganic Fe It is considered an acute-phase protein with a beneficial effect in inflammation . It was suggested that ceruloplasmin acts as a scavenger of OJ radicals, as it inhibited the reduction of Fe(III)-cytochrome c and of nitroblue tetrazolium in the presence of xanthine oxidase, acetaldehyde, and dioxygen as an OJ-generating system A mechanism without reduction of Cu , similar to that 

A weak dismutase activity with a second-order rate constant of 3 x 10 s  

In conclusion no other Cu protein has a superoxide dismutase activity comparable to that of (Cu,Zn)-SOD. 

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