Registries disease/outcome based

ATSDR. 1997. Volatile organic compounds in drinking water and adverse pregnancy outcomes. Interim report. United States Marine Corps Base Camp Lejeune, North Carolina, U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Atlanta, GA. 

Another major anatomical predictor of outcome in patients with CAD is the extent of atheromatous disease in the coronary artery tree. In the simplest categorization, patients can be separated into those with one-, two-, and three-vessel coronary disease based on the number of major epicardial vessels with significant coronary artery plaque. In the CASS Registry of medically-treated patients where the definition of clinically significant obstruction was a >70% reduction in the internal diameter of the vessel, the 12-year survival of patients with one-, two-, and three-vessel disease was 74%, 59%, and 40%, respectively (3). Stenosis of the left main artery >50% was also useful in predicting patient survival 12-year survival was 60% versus 49% for patients with two-vessel disease without and with left main disease respectively, and 41% and 35% for patients with three-vessel disease. As noted in the previous section, ejection fraction also strongly stratified survival in all three groups. 

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