Dirhodium -2-oxazolidinone-4-carboxylate

Chiral dirhodium(II) tetrakis(methyl-2-oxopyrrolidine-5-carboxylates) and dirhodium(ll) tetrakis(4-benzyl-2-oxazolidinones) have been studied to determine factors influencing the enantiocontrol in metal-carbene transformations. Doyle et al. used the Tektronix CAChe molecular modeling system to examine the steric control on the optical yields of cyclopropanation products.Details of the force field are not available in the open literature. The low energy conformation of the proposed metal-carbene intermediate predicted absolute configurations of the product that conflicted with experiment. However, when the metal-carbene was weakly bonded to styrene, the low energy conformer... 

Yields and enantioselectivities are low in reactions with disubstituted alkynes. Asymmetric synthesis of lactams A rhodium catalyst with a chiral oxazolidinone ligand, dirhodium(ll) tetrakis[methyl 2-oxazolidinone-4 (S)-carboxylate] (1), can effect... 

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