Direct cycloauration reactions

One of the most facile, direct cycloauration reactions is that of an [AuC14] source with (commercially available) 2-anilinopyridine. Reaction of Na[AuCl4] with... 

As described in Section II.A, the complex 2-(3-thienyl)pyridineAuCl3 6 undergoes direct cycloauration in refluxing MeCN/H20, but the 2-thienyl isomer 7 does not.14 However, reaction of 7 with Ag[BF4] in dichloromethane did give the desired product 9. 

However, cycloauration is, sometimes, difficult to achieve with direct activation of a C—H bond and transmetallation reaction of organomercury or organotin compounds with the appropriate gold compounds is, hence, frequently used. This procedure has been used with azobenzene, 36 A, A -dimethylbenzilamine,1937,1938 4,4 -dimethyl-2-phenyl-l, 3-oxaazoline,1938 1 - (dii zene,... 

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