Dipyridamole structure

Some azocane-substituted pyrazoline compounds have been reported as cannabinoid receptor modulators <2007W00009723, 2007WO131538>. An azocane derivative with a 3,3-diphenylpentane skeleton was reported to be an inhibitor of human 5a-reductase 1 <2007BMCL5414>. A dipyridamole analog having a bis-azocane structure was identified as a highly potent Nucleoside Transporter 1 inhibitor <2007JMC3906>. 

Presently, no structures of cilostazol or dipyridamole are bound to a PDE. Therefore, the precise mechanism of inhibition and the basis for their seieotivity are unknown. 

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