Diptoindonesin G C-H Arylation of Benzofuran

S Lithospermic Acid (Formation of Dihydrobenzofuran Using C-H Alkylation) 

4 Lithospermic Acid (Formation of Dihydrobenzofuran Using C-H Insertion and C-H Alkenylation at the C4 Position of Dihydrobenzofuran) 

113 in regio- and stereoselective fashion. After a few more transformations, the synthesis of (+)-morphine, the unnatural enantiomer of morphine, was completed in a total of 28 steps. 

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