Dipolar Couplings into Simulated Annealing Protocols

Incorporation of Dipolar Couplings into Simulated Annealing Protocols 

Dipolar couplings are very powerful restraints for structure determination of biomolecules and the determination of protein-protein or protein-ligand interactions [16]. They depend on the orientation of an internuclear vector, and its distance and the angular dependence is given by the following formula  

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