Dioxopurines

Derivatives of 2,4-dioxopurine, which may act as adenosine receptor antagonists, depending on the chemical structure. 

The electrochemical oxidation of hypoxanthine (261) in aqueous solution gave the intermediate 6,8-dioxopurine (262), which is more easily oxidized than 261, leading to 6,8-dioxopurinediimine (263).408 It is proposed that the nucleophilic attack of water occurs at the 4- or 5-position of 263, leading to the imino alcohols 264 or 265 [Eq. (138)]. These two compounds decompose by subsequent chemical or electrochemical reactions to the three major final products 5-imino-2,4-imidazoledione, 5-hydroxyhydantoin-5-carboxamide, and 4-amino-4-carboxyimidazol-5-one. 

DIOXOPURIN-7-YL) MERCURI) PROPYL) CARBAMOYL) -. SODIUM SALT... 

The interrelationship between the 2- and 8-positions is exemplified by 2-oxo-103 and 8-oxopurine, which are both converted by xanthine oxidase to 2,8-dioxopurine. Some unexpected results of oxidation can best be explained by assuming stereospecific factors. Thus, whereas purine, its 2-methyl, and its 2-amino derivatives give the 6-oxo derivatives, the 2-phenyl- and 2-oxopurines mentioned above oxidize at the 8-position.112... 

TRIMETHYL-2,6-DIOXOPURINE see CAK500 3,7,ll-TRIMETHYL-l,6,10-DODECATRIEN-3-YL ACETATE see NCN800... 

A fuller account of the complex alkylation of 6,8-dioxopurines has appeared... 

Synonyms 1,3,7-Trimethyl-2,6-dioxopurine 1,3,7-Trimethylxanthine Source Burgos-Solorzano, G. I. Brennecke,... 

Caffeine belongs to the family of heterocyclic compounds known as purines. It has the systematic name 3,7-dihydro-l,3,7-trimethyl-lH-purme-2,6-dione it is also known as 1,3,7-trimethylxanthme, and l,3,7-trimethyl-2,6-dioxopurine. Caffeine can be classified as an alkaloid, a term used for substances produced as end products of nitrogen metabolism in some plants. The chemical formula is C8H10N4O2. Caffeine has a molar mass of... 

Xanthine, 3f7-Dihydro-lH-purine-2,6-dion.ei 2.6-(lH 3H)-purinedione 2,6-dioxopurine. C5H4N402 mol wt 152.11, C 39.48%, H 2.63%, N 36.84%, O 21 04%. Occurs in animal organs, yeast, potatoes coffee beans, tea. First isolated from urinary bladder stones Beilstein 26, 447... 

Synonyms 3,7-dihydro-l,3,7-trimethyl-l/7-purine-2,6-dione 1,3,7- trimethylxan thine 1,3,7-trimethyl-2,6-dioxopurine methyl-theobromine guaranine theine... 

Consisting of caffeine and aU so-called caffeine analogues that include, but are not limited to, the following terms caffeine, guaranine, mateina, mateine, methyltheobromine, thein, theine, 1,3,7-trimethylxanthine, l,3,7-trimethyl-2,6-dioxopurine, and T-methyltheophylHne. 

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