1,2-Dioxetanes mass spectra

The oxidation of vitamin K hydroquinone monoanion (17) with labelled, 802 in THF leads to vitamin K oxide (18) in which the epoxide oxygen is fully labelled, hi addition, partial incorporation of 180 at the carbonyl oxygen is observed (on the basis of the mass spectrum).215 This is most readily explained by invoking a dioxetane intermediate (19) as opposed to the alternative intermediacy of a 2-hydroperoxide (20), where only the epoxide oxygen would be expected to be labelled. 

Fig. 2. (a) Full-scan MALDI-TOF mass spectrum of dioxetane lb (b) Full-scan MALDI-TOF mass spectrum of keto ester 2b... 

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See also in sourсe #XX -- [ ]

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