1.3.4- Dioxazolines, synthesis

Dioxazolines, synthesis, 30 271 Dioximes, technetium(III) complexes, 41 33-36 Dioxocyclam, 45 96 Dioxohexakis(trimethylsilylmethyl)-... 

The synthesis of 1,2,4-dioxazolines and 1,2,4-dioxazolidines is based on the use of singlet oxygen, ozone, or peroxides. Thus, photoaddition of O2 to 2-alkoxyoxazoles followed by a rearrangement leads to unstable 3-acyl-... 

An improved synthesis of 1,4,2-dioxazolines from hydroxamic acids 119 and 2,2-diethoxypropane in the presence of camphorsulfonic acid as an acidic catalyst via a transketalization reaction has been reported (Scheme 23)... 

Another approach for the synthesis of dioxazoline derivative 162 is achieved by Michael addition of benzohy-droxamic acid 161 to methyl propiolate, catalyzed by iV-methylmorpholine (Scheme 24) <2000TL7433>. 

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