Dimethylphenacyl esters

Klan, P., Pelliccioli, A.P., Pospisil, T. and Wirz, J. (2002) 2,5-Dimethylphenacyl esters A photoremovable protecting group for phosphates and sulfonic acids. Photochemical e[ Photobiological Sciences, 1, 920-923. 

Zabadal. M., PeUiccioh, A. R, Kldn, R, and Wirz, J., 2,5-Dimethylphenacyl esters a photoremovable protecting group for carboxylic acids, /. Phys. Chem. A, 105, 10329-10333, 2001. 

The Norrish Type II reactivity of the acetophenone derivatives (20) has been exploited as a new photoremovable protecting system for carboxylic acids. The irradiation affords the usual 1,5-biradicals that then release the acids (21) in the yields shown in parenthesis. Irradiation times are short. Klan and co-workers have described the photochemical reactivity of 1,5-dimethylphenacyl phosphoric and sulfonic esters. 

A series of 2,5-dimethylphenacyl (DMP) esters were photolyzed in benzene or methanol (Eq. (69.23)). 

---