2.4- Dimethylpentane-2,4-diol chromate

Dimethylpentane-2,4-diol chromate(VI) diester (1). The diol is prepared by reaction of diacetone alcohol with 2 equiv. of CH3Li (ether, -70-0°), 97% crude yield. The chromate ester (1) is obtained by reaction of the diol in CC14 with Cr03 after about 10 minutes P205 is added and then the clear solution is stored for use. 

Using chromium-based oxidants 2,4-Dimethylpentane-2,4-diol chromate(VI) diester, 122 Trimethylsilyl chlorochromate, 327 Using other oxidizing agents... 

Using chromium-based oxidants 2,4-Dimethylpentane-2,4-diol chromate(VI) diester, 122 Trimethylsilyl chlorochromate, 327 Using other oxidizing agents Bis(tributyltin) oxide, 41 Hydrogen hexachloroplatinate(IV)-Copper(II) chloride, 145 4-Methoxy-2,2,6,6-tetramethyl-1 -oxopiperidinium chloride, 183 Osmium tetroxide, 222 Potassium nitrosodisulfonate, 258 Samarium(II) iodide, 270 From alkenes by addition or cleavage reactions... 

Obtained in 70% yield from CrOj and TiCU in CH2CI2 with ultrasound irradiation for 2.5 h. It can be used in the Etard oxidation or converted into Cr02(0Bu >2 and the cyclic chromate of 2,5-dimethylpentane-2,5-diol for other oxidations. 

---