Dihydropyridylaluminum hydride

Dihydro-A-nortestosterone, 35 Dihydropyridylaluminum hydride, 75 3 a, 6a-Dihydroxy-5 /3-androstan-17-one, 415 3 a,6o -Dihydroxy-5j8-androstan- 17-one dinitrate, 415... 

Novel preferential reduction. Diaryl ketones are much more reactive toward Li-N-dihydropyridylaluminum hydride (formula s. 944) than are either dialkyl or arylalkyl ketones. This sequence is in contrast to that found with NaBH4 in isopropanol and appears to be without precedent in nucleophilic addition to carbonyl groups. E. and limitation s. P. T. Lansbury and J. O. Peterson, Am. Soc. 54, 1756 (1962). 

A novel hydrogenation technique has been introduced, in which both catalyst and hydrogen are prepared in situ These investigations have also yielded highly active carbon-supported catalysts. Preferential reduction of diaryl ketones can be achieved by using lithium N-dihydropyridylaluminum hydride . Base-sensitive 0X0 compounds can be reduced to hydroxy compounds by a 3-step sequence through diazo compounds Enamines can be hydro-genolyzed to alkenes with lithium aluminum hydride and aluminum chloride... 

---