Dihydrofolate reductase, domain structure

We demonstrate the latter approaeh on a small protein domain, which is homologous to proteins that are present in the protein data bank [86], As can be nicely seen in Fig. 55, rhodniin, which is homologous to other Kazal-type inhibitors, is found in the protein data bank. Here, the sequence homology is quite high. However, also structures with almost no sequence homologies are detected, as is the case for dihydrofolate reductase and D-xylose isomerase. 

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