2.3- Dihydro-5-oxaisothiazole pyridine

The synthesis of 2,3-dihydro-5-oxaisothiazole[5,4-fc]pyridine 321 was performed from monothiomalonamide (319) and methoxybutenone (85S861). 2-Thioxo-l,2-dihydropyridine-3-carboxamide 320 forming in the first stage (piperidine-acetate, EtOH, 10 h, yield 87%) was further oxidized to isothiazolopy-ridine 321, yield 95%. 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

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