Difluorophenylacetic acids

L. Zhou, Y. Wu, B. D. Johnson, R. Thompson, and J. M. Wyvratt, Chromatographic separation of 3,4-difluorophenylacetic acid and its positional isomers using five different techniques, J. Chromatogr. A 866 (2000), 281-292. 

C8H6BrCIO 2-bromo-1-(4-chlorophenyl)ethanone 536-38-9 25.00 1.6070 2 1285C ) C8H6F202 3,5-difluorophenylacetic acid 105184-38-1 25.00 1.3010 2... 

In an interesting study by Zhou et al. [1569], the separation of six positional isomers of difluorophenylacetic acid (2,3-, 2,4-, 2,5-, 2,6-, 3,4-, 3,5-) were ultimately baseline resolved on a base deactivated 25°C C,g column (X — 210nm) using a 95/5 water/acetonitrile with 15mM sodium phosphate at pH pp, , 6.5 mobile phase. 

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