Difficulties associated with vaccine development

A number of attributes of HIV and its mode of infection conspire to render development of an 

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The increasing prevalence of strains of P. falciparum that are resistant to chloroquine (CQ), a blood schizontocide which had been efficacious, safe, accessible and affordable, poses a serious problem for malaria control, predisposing Afiica to an unprecedented situation since the only affordable treatment options are rapidly losing therapeutic efficacy. Drug-resistant strains of P. falciparum are endemic in many areas of the world and the majority of conventional antimalarial drugs have been associated with treatment failure. These developments and the difficulty of creating efficient vaccines, coupled with adverse reactions to chemotherapy, underline the urgent need for novel, cheap, safe and... 

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