Different Oligopeptides and Oligonucleotides

Light-Directed Parallel Synthesis of Up to 250 000 Different Oligopeptides and Oligonucleotides 

The development of enzyme inhibitors based on oligopeptides makes it imperative to prepare a daunting number of oligopeptides with different sequences and to test their binding properties in order to find an optimally binding ligand. 

and 1 with lengths 1-10. Each peptide sequence is situated at one field of the (32 X 32) matrix. 

As light source, the authors used a mercury arc lamp, that required an exposure of 20 min 

Three critical questions must, however, be answered experimentally before a general application to affinity studies is recommended  

---