Diether linkers

Fig. 2. Application of the polyethylene glycol-co-monomethyl ether (MPEG) solid support with an a,a -dioxyxylyl (DOX) diether linker for oligosaccharide synthesis in solution.

Figure 5. Structure of a stilbene diether-linked hairpin. The linker is shown at top of structure with cylindrical bonds [26],...

Lewis and his co-workers have continued their investigations into DNA hairpins with a variety of stilbene diether linkages. In the present report they have examined systems based on the linkers (3) and (4). The rotaxane formed between the stilbene derivative (5) and a-cyclodextrin (CD) does not undergo ,Z-isomerization. Contrary to this the complex of (6) with the p-CD isomerizes slowly on irradiation. The behaviour of the stilbene (6) is different and irradiation in a-CD brings about isomerization with a quantum yield of 0.06 for the E,Z process. The quantum yield for the reverse isomerization is 0.71. These values are to be compared with 0.17 and 0.79 for the isomerization in solution. The authors suggest that the irradiation of (6) in the CD brings about a movement... 

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