3,4-Dideoxy-pentonic acid

PHOTOINDUCED-ADDITION OF METHANOL TO (5S)-(5-0-tert-BUTYLDIMETHYLSILOXYMETHYL)FURAN-2(5H)-ONE (4R,5S)-4-HYDROXYMETHYL-(5-0-tert-BUTYLDIMETHYLSILOXYMETHYL)FURAN-2(5H)-ONE (2(5H)-Furanone, 5-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, (S)-and D-erythro-Pentonic acid, 2,3-dideoxy-5-0-[(1,1-dimethylethyl)dimethylsilyl]-3-(hydroxymethyl)-, y-lactone)... 

R,5S)-4-HYDR0XYMETHYL-(5-0-tert-BUTYLDIMETHYLSIL0XYMETHYL)FURAN-2(5H)-ONE D-erythro-PENTONIC ACID, 2.3-DIDEOXY-5-0-[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]-3-HYDROXYMETHYL)-,... 

A number of synthesis of amino-sugars from chiral non-carbohydrate starting materials have been reported. A reaction sequence used previously to synthesize 2-amino-2-deoxy-D-ribose from 2,3-0-isopropylidene-D-glyceraldehyde (V0I.I6, p.92-3) has been improved K) achieve better stereoselectivity in the initial aldol condensation used to extend the chain by two carbon atoms. The synthesis of a 6,6,6-trifluoro-L-daunosamine derivative from 2,3-0-cyclohexylidene-D-glyceraldehyde is covered in Chapter 8, and of 2,5-dideoxy-2,5-imino-pentonic acids from tartaric acid in Chapter 16. 

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