1.5- Dichloropentane-3-one

Hydrolysis. The crude 1.5-dichloropentane-3-one obtained as a dark-brown oil (555-585 g.) by the aluminum chloride-catalyzed addition of 3-chloropropiony] chloride to ethylene in methylene chloride is hydrolyzed in two equal batches. For each batch a 3-1. three-necked, round-bottomed flask with a thermometer, reflux condenser, and 250-ml. dropping funnel is charged with 600 ml. ofwater, 6(X)mI. ofdioxane, and 510 g. (3.70 moles) of sodium dihydrogen phosphate monohydratc and two or three No. 12... 

In the first step, 3-chloropropionyl chloride is converted to 1,5 dichloropentane-3-one via Friedel-Crafts acylation in presence of ethylene at 20°C as described by... 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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